4-甲氧基硫代苯甲酰胺
化合物
4-甲氧基硫代苯甲酰胺是一种有机硫化合物，化学式为C8H9NOS。它可由4-甲氧基苯甲酰胺和五硫化二磷反应制得。[3]在三乙胺存在下，它和碘、氧气反应，可以得到4-甲氧基苯甲腈。[4]
| 4-甲氧基硫代苯甲酰胺 | |
|---|---|
| 识别 | |
| CAS号 | 2362-64-3 
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| SMILES |
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| 性质 | |
| 化学式 | C8H9NOS |
| 摩尔质量 | 167.23 g·mol−1 |
| 熔点 | 148-149.5 °C[1] |
| 结构 | |
| 晶体结构 | P212121（173 K）[2] |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
延伸阅读
编辑- Kevin S. Eccles; et al. Crystal Landscape of Primary Aromatic Thioamides. Cryst. Growth Des. 2014, 14, 6, 2753–2762. doi:10.1021/cg401891f.
参考文献
编辑- ^ Eleftherios P. Papadopoulos. Friedel-Crafts thioacylation with ethoxycarbonyl isothiocyanate. One-step synthesis of aromatic thioamides. J. Org. Chem. 1976, 41, 6, 962–965. doi:10.1021/jo00868a013.
- ^ Saqib Ali; et al. 4-Methoxybenzenecarbothioamide. Acta Cryst E. 2010. 66 (6). o1272. doi:10.1107/S1600536810015825.
- ^ Wang, Liang; et al. Synthesis and antibacterial activities of pleuromutilin derivatives with thiazole-5-carboxamide and thioether moiety. Journal of Chemical Research (2011), 35(5), 313-316. doi:10.3184/174751911x13057375208346.
- ^ Murata, Yuki; et al. Synthesis of nitriles via the iodine-mediated dehydrosulfurization of thioamides. Chemical & Pharmaceutical Bulletin (2020), 68(7), 679-681. doi:10.1248/cpb.c20-00228.