2-甲基-5-羟色胺

化合物

2-甲基-5-羟色胺(英語:2-Methyl-5-hydroxytryptamine或2-Methylserotonin、2-Methyl-5-HT)是一种色胺衍生物神经递质血清素密切相关[1][2][3]

2-甲基-5-羟色胺
识别信息
  • 3-(2-aminoethyl)-2-methyl-1H-indol-5-ol
CAS号78263-90-8  checkY
PubChem CID
IUPHAR/BPS
ChemSpider
KEGG
ChEBI
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.231.402 編輯維基數據鏈接
化学信息
化学式C11H14N2O
摩尔质量190.242 g/mol
3D模型(JSmol英语JSmol
  • Oc1cc2c(cc1)nc(c2CCN)C
  • InChI=1S/C11H14N2O/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7/h2-3,6,13-14H,4-5,12H2,1H3 checkY
  • Key:WYWNEDARFVJQSG-UHFFFAOYSA-N checkY

另见

编辑

参考文献

编辑
  1. ^ Elz S, Zimmermann H, Rehse K. Selectivity of sterically fixed tryptamine and 5-methoxytryptamine derivatives for serotonin receptor subtypes, II: Structure-activity relationships and in vitro pharmacology of N-alkyl- and N,N-dialkyl-3- indolylbicyclo-[2.2.1]-heptane-2-amines.. Arch Pharm (Weinheim). 1993, 326 (11): 893–899. PMID 8274071. doi:10.1002/ardp.19933261110. 
  2. ^ Craig DA, Eglen RM, Walsh LK, Perkins LA, Whiting RL, Clarke DE. 5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum.. Naunyn Schmiedebergs Arch Pharmacol. 1990, 342 (1): 9–16. PMID 2402303. 
  3. ^ Glennon RA, Dukat M, Westkaemper RB. Serotonin Receptor Subtypes and Ligands. American College of Neurophyscopharmacology. 2000-01-01 [2008-04-11]. (原始内容存档于2008-04-21).