中脑边缘通路
此條目可参照英語維基百科相應條目来扩充。 (2019年2月25日) |
中脑边缘通路（mesolimbic pathway）又称奖赏途径（reward pathway），是脑中的多巴胺通路[1]。此通路連接中腦的腹側被蓋區以及前脑基底核內的纹状体。紋狀體中包括有伏隔核及嗅節結[2]。
參考文獻
编辑- ^ Dreyer JL. New insights into the roles of microRNAs in drug addiction and neuroplasticity. Genome Med. 2010, 2 (12): 92. PMC 3025434
. PMID 21205279. doi:10.1186/gm213.
- ^ Ikemoto S. Brain reward circuitry beyond the mesolimbic dopamine system: a neurobiological theory. Neurosci Biobehav Rev. 2010, 35 (2): 129–50. PMC 2894302 . PMID 20149820. doi:10.1016/j.neubiorev.2010.02.001.
Recent studies on intracranial self-administration of neurochemicals (drugs) found that rats learn to self-administer various drugs into the mesolimbic dopamine structures–the posterior ventral tegmental area, medial shell nucleus accumbens and medial olfactory tubercle. ... In the 1970s it was recognized that the olfactory tubercle contains a striatal component, which is filled with GABAergic medium spiny neurons receiving glutamatergic inputs form cortical regions and dopaminergic inputs from the VTA and projecting to the ventral pallidum just like the nucleus accumbens
Figure 3: The ventral striatum and self-administration of amphetamine （页面存档备份，存于互联网档案馆）
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